Cydectin 10% LA Solution for Injection for Cattle 50ml

Moxidectin is a second generation macrocyclic lactone of the milbemycin family.

Administration

The 50 ml vial stoppers must not be broached more than 20 times. Shake vigorously before use.

To ensure administration of a correct dosage, bodyweight should be determined as accurately as possible; accuracy of the dosing should be checked.

The injection should be given subcutaneously in the loose tissues on the dorsal surface of the ear, just distal to the distal edge of the auricular cartilage. The dorsal (outer) surface of the ear should first be cleansed with antiseptic and allowed to briefly air dry. Palpate the edge of the auricular cartilage closest to the head, on the dorsal (hairy) surface of the ear. From this landmark, taking care to avoid blood vessels (artery, vein), the needle should be inserted subcutaneously starting at a point approximately 3 to 3.5 cm distal to this edge (away from the head) and directed towards the base of the ear and the needle advanced to the hub. At this point, gently aspirate the syringe to confirm that the needle is not in a blood vessel. Upon injection, the resulting depot should reside just distal to the edge of the auricular cartilage. Following administration, the needle is withdrawn from the skin as pressure is applied for several seconds with the thumb at the point of insertion.

Diagram: Ear injection procedureThe injection site is approximately 3.5 cm (1.5 inches) distal to the distal edge of the ear cartilage..Use one hand to grasp and steady the ear.

Inject subcutaneously using an 18 gauge x 1 inch needle.Inject contents. Depot should be just distal to the distal edge of the auricular cartilage.

Apply pressure at the point of insertion as the needle is withdrawn from the skin to help seal the opening.

Due to the long lasting protection against Dictyocaulus viviparus and the stomach worms, Ostertagia ostertagi and Haemonchus placei, a single treatment with the formulation at turn-out helps control parasitic bronchitis (lungworm) and parasitic gastro-enteritis throughout the grazing season by reducing the build-up of infective larvae on pasture associated with these parasites. For best results the injection should be given to each calf of target weight to be grazed together immediately prior to being turned out to pasture. Animals should be set stocked throughout the grazing season or moved to a pasture which has not been grazed by other cattle earlier in the season.

In cattle weighing from 100 to 500 kg bodyweight, CYDECTIN 10% LA is indicated for the treatment and prevention of mixed infestations by the following gastro-intestinal nematodes, respiratory nematodes and certain arthropod parasites:

Adult and immature gastro-intestinal nematodes •Haemonchus placei •Haemonchus contortus •Ostertagia ostertagi (including inhibited larvae) •Trichostrongylus axei •Trichostrongylus colubriformis •Nematodirus helvetianus (adults only) •Nematodirus spathiger •Cooperia surnabada •Cooperia oncophora •Cooperia pectinata •Cooperia punctata •Oesophagostomum radiatum •Bunostomum phlebotomum (adults only) •Chabertia ovina (adults only) •Trichuris spp. (adults only) Adult and immature respiratory tract nematode •Dictyocaulus viviparus Warble grubs (migrating larvae) •Hypoderma bovis •Hypoderma lineatum Lice •Linognathus vituli •Haematopinus eurysternus •Solenopotes capillatus •Bovicola bovis (aid in control) Mange mites •Sarcoptes scabiei •Psoroptes ovis •Chorioptes bovis (aid in control)

CYDECTIN 10% LA has a persistent action and protects cattle for a certain duration against infection or re-infection with the following parasites for the period indicated:

Species Protection period (days) Dictyocaulus viviparus 120 Ostertagia ostertagi 120 Haemonchus placei 90 Oesophagostomum radiatum 150 Trichostrongylus axei 90 Linognathus vituli 133

The product is effective against Hypoderma larvae at the time of treatment but its persistent activity against Hypoderma has not been evaluated.

If the product is given before the end of the fly season complimentary treatment with a product effective against Hypoderma may be required.

Persistent efficacy periods have not been established for parasite species other than those included in the above list.

Therefore re-infection of animals on pasture contaminated by parasites other than these remains possible before the end of the 90 day minimum persistency period demonstrated for specific species.